Novel, potent THC/anandamide (hybrid) analogs
نویسندگان
چکیده
منابع مشابه
Novel, potent THC/anandamide (hybrid) analogs.
The structure-activity relationship (SAR) of the end pentyl chain in anandamide (AEA) has been established to be very similar to that of Delta(9)-tetrahydrocannabinol (Delta(9)-THC). In order to broaden our understanding of the structural similarities between AEA and THC, hybrid structures 1-3 were designed. In these hybrids the aromatic ring of THC-DMH was linked to the AEA moiety through an e...
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ژورنال
عنوان ژورنال: Bioorganic & Medicinal Chemistry
سال: 2007
ISSN: 0968-0896
DOI: 10.1016/j.bmc.2007.08.039